The Effect of Angiotensin Converting Enzymes Inhibitors (ACEIs) on Type 2 Diabetes Mellitus (DM): Education on Prevention and Treatment

Abstract

The incidence of diabetes is currently predicted to be about 6.4% worldwide, and in the past two decades alone there has been a dramatic rise in the diagnosis of type 2 diabetes mellitus. Diabetes Mellitus (DM) affects more than 170 million adults worldwide. Current World Health Organization (WHO) predicts that 350 million individuals worldwide will have diabetes, by the year 2030. 1 The risk of death among patients with diabetes mellitus is almost double that with people without diabetes mellitus. Diabetes has been found to be a major cause for many cardiovascular diseases such as MI and angina. An internet-based search method was used in the systematic literature review of the study. This method included searching, collecting and evaluating stages. A manual review of the bibliographies of the important primary articles and review articles was also performed to identify any additional relevant studies. Results indicate that the use of ACEIs and ARBs has been found to be effective in preventing and delaying the onset of having new DM. Also it was found that ACEIs are better in preventing DM than the B-Blockers and diuretics. B-blockers and diuretics have been shown to decrease insulin sensitivity.